Pr. Quentin DENOST

• 2019 - 2022 : Professeur des Universités – Praticien Hospitalier, PU-PH, CHU de Bordeaux
• 2016 - 2019: Maître de Conférences – Praticien Hospitalier, MCU-PH, CHU de Bordeaux
• 2015 : International Clinical and Research Fellowship : 
  • Royal Prince Alfred Hospital – Sydney – Janvier-Juin 2015
  • Royal Mardsen Hospital – Londres) – Juillet-Decembre 2015
• 2011 - 2015 : Chef de Clinique – Assistant des hôpitaux ; CHU de Bordeaux 

• 2013 : Diplôme d’Etudes Spécialisées Complémentaire (DESC) oncologie, option chirurgie
• 2013 : Diplôme d’Etudes Spécialisées Complémentaire (DESC) de chirurgie viscérale et digestive
• 2011 : Diplôme d’Etudes Spécialisées (DES) de chirurgie générale, Université Bordeaux Segalen
• 2011 : MD, Doctorat en médecine, Université Bordeaux Segalen, Mention très honorable

• 2018 : Habilitation à Diriger une Recherche (HDR)
• 2014 : PhD, Doctorat en Biologie cellulaire et physiologie, Université Bordeaux Segalen
• 2010 : Master II de Radiophysique et Imagerie Médicale, Université Paul Sabatier Toulouse

• 2015 : Prix de la Recherche Clinique – Jeune talent chirurgical ; Académie Nationale de Chirurgie
• 2015 : Bourse de mobilité Société Française de Chirurgie Digestive (SFCD)
• 2015 : Bourse de Recherche Jeune Chercheur Unicancer
• 2009 : Bourse de Recherche Association pour la Recherche sur le Cancer (ARC)

-Publications Année 2024

Treatment techniques for rectovaginal fistulas after low rectal resection for deep endometriosis.
Potolicchio A, Jehaes C, Merlot B, Assenat V, Dennis T, Roman H, Francois MO, Denost Q.Tech Coloproctol. 2024 Apr 29;28(1):51.

Rectovaginal Fistula: What is the Role of Martius Flap and Gracilis Muscle Interposition in the Therapeutic Strategy?
Pastier C, Loriau J, Denost Q, O'Connell L, Challine A, Collard M, Debove C, Chafai N, Parc Y, Lefevre JH.Dis Colon Rectum. 2024 Apr 23. 

Contemporary results from the PelvEx collaborative: improvements in surgical outcomes for locally advanced and recurrent rectal cancer.
PelvEx Collaborative.Colorectal Dis. 2024 Apr 2. 

Combined Robotic Transanal Transection Single-Stapled Technique in Ultralow Rectal Endometriosis Involvement Associated With Parametrial and Vaginal Infiltration.
D'Ancona G, Merlot B, Denost Q, Angioni S, Dennis T, Roman H.J Minim Invasive Gynecol. 2024 Apr;31(4):267-268.

Tips and tricks: robotic low anterior resection - A video vignette.
Sánchez-Rodríguez M, Khan J, Denost Q, Tejedor P.Colorectal Dis. 2024 Mar 31. 

The empty pelvis syndrome: a core data set from the PelvEx collaborative.
PelvEx Collaborative.Br J Surg. 2024 Mar 2;111(3):znae042.

Multicentre cohort study evaluating clinical, oncological and functional outcomes following robotic rectal cancer surgery-the EUREKA collaborative: trial protocol.
Fleming CA, Duhoky R, Geitenbeek RTJ, Moussion A, Bouazza N, Khan J, Cotte E, Dubois A, Rullier E, Hompes R, Denost Q, Rouanet P, Consten ECJ; EUREKA collaborative.BJS Open. 2024 Mar 1;8(2):zrae019.

Beating the empty pelvis syndrome: the PelvEx Collaborative core outcome set study protocol.
PelvEx Collaborative.BMJ Open. 2024 Feb 5;14(2):e076538.

Can shared medical decision-making help to solve the complex equation involved in the choice of optimal treatment for low rectal cancer?
Brouquet A, Denost Q.J Visc Surg. 2024 Feb;161(1):3-5.

Local Regrowth and the Risk of Distant Metastases Among Patients Undergoing Watch-and-Wait for Rectal Cancer: What Is the Best Control Group? Multicenter Retrospective Study.
São Julião GP, Fernández LM, Vailati BB, Habr-Gama A, Azevedo JM, Santiago IA, Parés O, Parvaiz A, Vendrely V, Rullier A, Rullier E, Denost Q, Perez RO.Dis Colon Rectum. 2024 Jan 1;67(1):73-81.

-Publications Année 2023

IDEAL Stage 2a/b prospective cohort study of transanal transection and single-stapled anastomosis for rectal cancer.
Harji D, Fernandez B, Boissieras L, Celerier B, Rullier E, Denost Q.Colorectal Dis. 2023 Dec;25(12):2346-2353.

Low-impact laparoscopy in colorectal resection-A multicentric randomised trial comparing low-pressure pneumoperitoneum plus microsurgery versus low-pressure pneumoperitoneum alone: The PAROS II trial.
Marichez A, Eude A, Martenot M, Celerier B, Capdepont M, Rullier E, Denost Q, Fernandez B.Colorectal Dis. 2023 Dec;25(12):2403-2413.

Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group.Br J Surg. 2023 Nov 9;110(12):1863-1876

Empty pelvis syndrome: PelvEx Collaborative guideline proposal.
PelvEx Collaborative.Br J Surg. 2023 Nov 9;110(12):1730-1731. 

Robotic-assisted versus conventional laparoscopic approach in patients with large rectal endometriotic nodule: the evaluation of safety and complications.
Volodarsky-Perel A, Merlot B, Denost Q, Dennis T, Chanavaz-Lacheray I, Roman H.Colorectal Dis. 2023 Nov;2

The Crying Need for a Better Response Assessment in Rectal Cancer.
Amintas S, Giraud N, Fernandez B, Dupin C, Denost Q, Garant A, Frulio N, Smith D, Rullier A, Rullier E, Vuong T, Dabernat S, Vendrely V.
Curr Treat Options Oncol. 2023 Nov;24(11):1507-1523.  

Local excision after neoadjuvant chemoradiotherapy for mid and low rectal cancer: a multicentric French study from the GRECCAR group
Calmels M, Labiad C, Lelong B, Lefevre JH, Tuech JJ, Benoist S, Mège D, Denost Q, Panis Y.
Colorectal Dis. 2023 Oct;25(10):1973-1980. doi: 10.1111/codi.16742. Epub 2023 Sep 7.

International standardization and optimization group for intersphincteric resection (ISOG-ISR) : modified Delphi consensus on anatomy, definition, indication surgical technique, specimen description and functional outcome.
Piozzi GN, Khobragade K, Aliyev V, Asoglu O, Bianchi PP, Butiurca VO, Chen WT, Cheong JY, Choi GS, Coratti A, Denost Q, Fukunaga Y, Gorgun E, Guerra F, Ito M, Khan JS, Kim HJ, Kim JC, Kinugasa Y, Konishi T, Kuo LJ, Kuzu MA, Lefevre JH, Liang JT, Marks J, Molnar C, Panis Y, Rouanet P, Rullier E, Saklani A, Spinelli A, Tsarkov P, Tsukamoto S, Weiser M, Kim SH.Colorectal Dis. 2023 Aug 10.

Low anterior resection syndrome after rectal resection management : multicentre randomized clinical trial of transanal irrigation with a dedicated device (cone catheter) versus conservative bowel management.
Meurette G, Faucheron JL, Cotte E, Denost Q, Portier G, Loriau J, Hansen AW, Vicaut E, Lakkis Z.Br J Surg. 2023 Aug 11

MRI restaging of rectal cancer : The RAC (Response-Anal canal-CRM) analysis joint consensus guidelines of the GRERCAR and GRECCAR groups.
Nougaret S, Rousset P, Lambregts DMJ, Maas M, Gormly K, Lucidarme O, Brunelle S, Milot L, Arrivé L, Salut C, Pilleul F, Hordonneau C, Baudin G, Soyer P, Brun V, Laurent V, Savoye-Collet C, Petkovska I, Gerard JP, Cotte E, Rouanet P, Catalano O, Denost Q, Tan RB, Frulio N, Hoeffel C.Diagn Interv Imaging. 2023 Jul-Aug

Learning curve robotic-assisted total mesorectal excision : a multicentre, prospective study.
Arquillière J, Dubois A, Rullier E, Rouanet P, Denost Q, Celerier B, Pezet D, Passot G, Aboukassem A, Colombo PE, Mourregot A, Carrere S, Vaudoyer D, Gourgou S, Gauthier L, Cotte E.Colorectal Dis. 2023 Jul 31

Is Delaying a Coloanal Anastomosis the Ideal Solution for Rectal Surgery : Analysis of a Multicentric Cohort of 564 Patients from the GRECCAR.
Collard MK, Rullier E, Tuech JJ, Sabbagh C, Souadka A, Loriau J, Faucheron JL, Benoist S, Dubois A, Dumont F, Germain A, Manceau G, Marchal F, Sourrouille I, Lakkis Z, Lelong B, Derieux S, Piessen G, Laforest A, Venara A, Prudhomme M, Brigand C, Duchalais E, Ouaissi M, Lebreton G, Rouanet P, Mège D, Pautrat K, Reynolds IS, Pocard M, Parc Y, Denost Q, Lefevre JH; GRECCAR Group.Ann Surg. 2023 Jul 31

Clinical consequences of diagnostic variability in the histopathological evaluation of early rectal cancer.
Smits LJH, van Lieshout AS, Bosker RJI, Crobach S, de Graaf EJR, Hage M, Laclé MM, Moll FCP, Moons LMG, Peeters KCMJ, van Westreenen HL, van Grieken NCT, Tuynman JB; TESAR research group.Eur J Surg Oncol. 2023 Jul

Robotic-assisted soft-tissue pelvic exenteration for primary and recurrent pelvic tumors : IDEAL stage 2a evaluation. 
Fleming CA, Harji D, Salut C, Cauvin T, Robert G, Denost Q.Br J Surg. 2023 Jul 17

Can shared medical decision-making help to solve the complex equation involved in the choice of optimal treatment for low rectal cancer ? 
Brouquet A, Denost Q.J Visc Surg. 2023 Jul 25

Local Regrowth and the Risk of Distant Metastases Among Patients Undergoing Watch-and-Wait for Rectal Cancer : What Is the Best Control Group ? Multicenter Retrospective Study.
São Julião GP, Fernández LM, Vailati BB, Habr-Gama A, Azevedo J, Santiago I, Parés O, Parvaiz A, Vendrely V, Rullier A, Rullier E, Denost Q, Perez RO.Dis Colon Rectum. 2023 Jul 25

Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage : Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group.Ann Surg. 2023 Jul 27

Parallel, component training in robotic total mesorectal excision. 
Harji D, Aldajani N, Cauvin T, Chauvet A, Denost Q.J Robot Surg. 2023 Jun

An analysis of feasibility of robotic colectomy : post hoc analysis of a phase III randomised controlled trial.
Fleming CA, Celarier S, Fernandez B, Cauvin T, Célérier B, Denost Q.J Robot Surg. 2023 Jun

Comparison between preoperative chemoradiotherapy and lateral pelvic lymph node dissection in clinical T3 low rectal cancxer without enlarged lateral lymph nodes.
Tsukada Y, Rullier E, Shiraishi T, Capdepont M, Sasaki T, Celerier B, Denost Q, Ito M.Colorectal Dis. 2023 Jun

Robotic assisted rectal disk excision : the 3-cm diameter cut off may be abandoned.
D'Ancona G, Merlot B, Denost Q, Roman H.Fertil Steril. 2023 May

Integrating a tumour appropriate transanal or robotic assisted approach to total mesorectal excision in high-volume rectal cancer practice is safe and cost-effective.
Fleming C, Fernandez B, Boissieras L, Cauvin T, Denost Q.J Robot Surg. 2023 Apr 26.

A phase III randomized trial evaluating the quality of life impact of a tailored versus systematic use of defunctioning ileostomy following total mesorectal excision for rectal cancer-GRECCAR 17 trial Protocol. Denost Q.
Sylla D, Fleming C, Maillou-Martinaud H, Preaubert-Hayes N, Benard A; GRECCAR group.Colorectal Dis. 2023 Mar

Excision of Deep Rectovaginal Endometriosis Nodules with Large Infiltration of Both Rectum and Vagina : What Is a Reasonable Rate of Preventive Stoma ? A comparative Study. 
Roman H, Dennis T, Forestier D, François MO, Assenat V, Chanavaz-Lacheray I, Denost Q, Merlot B.J Minim Invasive Gynecol. 2023 Feb

An International Multicenter Prospective Study Evaluating the Long-term Oncological Impact of Adjuvant Chemotherapy in ypN+ Rectal Cancer. 
Denost Q, Fleming CA, Burghgraef T, Celerier B, Geitenbeek R, Rullier E, Tuynman J, Consten E, Hompes R; Dutch MIRECA Collaborative Group (Pubmed Citable).Ann Surg. 2023 Feb

Robotic-assisted enterovaginoplasty reconstruction folowing a posterior pelvic exenteration - a video vignette. 
Fleming CA, Chauvet A, Cauvin T, Denost Q. Colorectal Dis. 2023 Jan;25

Feasability study of a Response Surveillance Program in locally advanced mid and low rectal cancer to increase organ preservation.
Boubaddi M, Fleming C, Vendrely V, Frulio N, Salut C, Rullier E, Denost Q.Eur J Surg Oncol. 2023 Jan

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